Here we argue that a multidisciplinary research approach, such as currently practised in the field of developmental cognitive neuroscience, is key to maintaining current momentum and to future-proof the field of microbiome-gut-brain research. Moreover, such a comprehensive approach will also bring us closer to our aims of translation and targeted intervention approaches to improve mental health and well-being.

This article presents a model for regulating cognitive enhancement devices. Recently, it has become very easy for individuals to purchase devices which directly modulate brain function. For example, transcranial direct current stimulators are increasingly being produced and marketed online as devices for cognitive enhancement. Despite posing risks in a similar way to medical devices, devices that do not make any therapeutic claims do not have to meet anything more than basic product safety standards. We present the case for extending existing (...) medical device legislation to cover CEDs. Medical devices and CEDs operate by the same or similar mechanisms and pose the same or similar risks. This fact coupled with the arbitrariness of the line between treatment and enhancement count in favour of regulating these devices in the same way. In arguing for this regulatory model, the paper highlights potential challenges to its implementation, and suggests solutions. (shrink)

Tzelgov and colleagues [Tzelgov, J., Meyer, J., and Henik, A. . Automatic and intentional processing of numerical information. Journal of Experimental Psychology: Learning, Memory and Cognition, 18, 166–179.], offered the existence of the laterality effect as a post-hoc explanation for their results. According to this effect, numbers are classified automatically as small/large versus a standard point under autonomous processing of numerical information. However, the genuinity of the laterality effect was never examined, or was confounded with the numerical distance effect. In (...) the current study, I controlled the numerical distance effect and observed that the laterality effect does exist, and affects the processing of automatic numerical information. The current results suggest that the laterality effect should be taken into account when using paradigms that require automatic numerical processing such as Stroop-like or priming tasks. (shrink)

Are small and large numbers represented similarly or differently on the mental number line? The size effect was used to argue that numbers are represented differently. However, recently it has been argued that the size effect is due to the comparison task and is not derived from the mental number line per se. Namely, it is due to the way that the mental number line is mapped onto the task-relevant output component. Here synesthesia was used to disentangle these two alternatives. (...) In two naming experiments a digit-color synesthete showed that the congruity effect was modulated by number size. These results support the existence of a mental number line with a vaguer numerical representation as numbers increase in size. In addition, the results show that in digit-color synesthesia, colors can evoke numerical representation automatically. (shrink)

The commentators have raised many pertinent points that allow us to refine and clarify our view. We classify our response comments into seven sections: automaticity; developmental and educational questions; priming; multiple representations or multiple access(?); terminology; methodological advances; and simulated cognition and numerical cognition. We conclude that the default numerical representations are not abstract.

Davis called for “extreme caution” in the use of non-invasive brain stimulation to treat neurological disorders in children, due to gaps in scientific knowledge. We are sympathetic to his position. However, we must also address the ethical implications of applying this technology to minors. Compensatory trade-offs associated with NIBS present a challenge to its use in children, insofar as these trade-offs have the effect of limiting the child’s future options. The distinction between treatment and enhancement has some normative force here. (...) As the intervention moves away from being a treatment toward being an enhancement—and thus toward a more uncertain weighing of the benefits, risks, and costs—considerations of the child’s best interests diminish, and the need to protect the child’s autonomy looms larger. NIBS for enhancement involving trade-offs should therefore be delayed, if possible, until the child reaches a state of maturity and can make an informed, personal decision. NIBS for treatment, by contrast, is permissible insofar as it can be shown to be at least as safe and effective as currently approved treatments, which are themselves justified on a best interests standard. (shrink)

ObjectiveProcessing Speed, the ability to perceive and react fast to stimuli in the environment, has been shown to be impaired in children with attention deficit hyperactivity disorder. However, it is unclear whether PS can be improved following targeted treatments for ADHD. Here we examined potential changes in PS following application of transcranial electric stimulation combined with cognitive training in children with ADHD. Specifically, we examined changes in PS in the presence of different conditions of mental fatigue.MethodsWe used a randomized double-blind (...) active-controlled crossover study of 19 unmedicated children with ADHD. Participants received either anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex or transcranial random noise stimulation, while completing CT, and the administration order was counterbalanced. PS was assessed before and after treatment using the MOXO-CPT, which measures PS in the presence of various conditions of mental fatigue and cognitive load.ResultstRNS combined with CT yielded larger improvements in PS compared to tDCS combined with CT, mainly under condition of increased mental fatigue. Further improvements in PS were also seen in a 1-week follow up testing.ConclusionThis study provides initial support for the efficacy of tRNS combined with CT in improving PS in the presence of mental fatigue in pediatric ADHD. (shrink)

Numbers are vital to so many areas of life: in science, economics, sports, education, and many aspects of everyday life from infancy onwards. This handbook brings together the different research areas that make up the vibrant field of numerical cognition in one comprehensive and authoritative volume.

In their target article, Rips et al. have presented the view that there is no necessary dependency between natural numbers and internal magnitude. However, they do not give enough weight to neuroimaging and neuropsychological studies. We provide evidence demonstrating that the acquisition of natural numbers depends on magnitude representation and that natural numbers develop from a general magnitude mechanism in the parietal lobes.

Cohen Kadosh & Walsh (CK&W) neglect the solid empirical evidence for a convergence of notation-specific representations onto a shared representation of numerical magnitude. Subliminal priming reveals cross-notation and cross-modality effects, contrary to CK&W's prediction that automatic activation is modality and notation-specific. Notation effects may, however, emerge in the precision, speed, automaticity, and means by which the central magnitude representation is accessed.

The study of neuronal specialisation in different cognitive and perceptual domains is important for our understanding of the human brain, its typical and atypical development, and the evolutionary precursors of cognition. Central to this understanding is the issue of numerical representation, and the question of whether numbers are represented in an abstract fashion. Here we discuss and challenge the claim that numerical representation is abstract. We discuss the principles of cortical organisation with special reference to number and also discuss methodological (...) and theoretical limitations that apply to numerical cognition and also to the field of cognitive neuroscience in general. We argue that numerical representation is primarily non-abstract and is supported by different neuronal populations residing in the parietal cortex. (shrink)

Numbers are fundamental to our understanding of, and survival in, the environment. Not surprisingly, numbers represent an important psychological dimension in triggering synaesthetic experiences, such as in digit-colour synaesthesia, or number-space synaesthesia. Another important consideration is directionality in synaesthesia, in that we might ask whether the stimulus and response in any given synaesthetic variant can also work on the opposite way. Most studies have documented the typical direction of the synaesthetic experience from the inducer to the concurrent. However, it seems (...) that some synaesthetes do show bi-directionality, that is, their concurrent might also trigger the inducer either at an implicit level, or even at the explicit level that reaches perceptual awareness. We discuss these two issues in this book chapter. We will first explore synesthesia and automaticity where numbers are concerned, followed by a discussion on synaesthesia and directionality. (shrink)

Numbers are vital to so many areas of life: in science, economics, sports, education, and many aspects of everyday life from infancy onwards. This handbook brings together the different research areas that make up the vibrant field of numerical cognition in one comprehensive and authoritative volume.

In this commentary we make two rejoinders to Jung & Haier (J&H). First, we highlight the response selection component in tasks as a confounding variable that may explain the parieto-frontal involvement in studies of human intelligence. Second, we suggest that efficient response selection may be an integral part of the definition of intelligence.

Number-form synesthetes consciously experience numbers in spatially-defined locations. For non-synesthete individuals, a similar association of numbers and space appears in the form of an implicit mental number line as signified by the distance effect–reaction time decreases as the numerical distance between compared numbers increases. In the current experiment, three number-form synesthetes and two different non-synesthete control groups performed a number comparison task. Synesthete participants exhibited a sizeable distance effect only when presented numbers were congruent with their number-form. In contrast, the (...) controls exhibited a distance effect regardless of congruency or presentation type. The findings suggest that: number-form synesthesia impairs the ability to represent numbers in a flexible manner according to task demands; number-form synesthesia is a genuine tangible experience, triggered involuntarily; and the classic mental number line can be more pliable than previously thought and appears to be independent of cultural-lingo direction. (shrink)

We concur with Cohen Kadosh & Walsh (CK&W) that representation of numbers in the parietal cortex is format dependent. In addition, we suggest that all formats do not automatically, and equally, access analog magnitude representation in the intraparietal sulcus (IPS). Understanding how development, learning, and context lead to differential access of analog magnitude representation is a key question for future research.

Cohen Kadosh, Tzelgov, and Henik [Cohen Kadosh, R., Tzelgov, J., and Henik, A. (2008). A synesthetic walk on the number line: The size effect. Cognition, 106, 548-557] present a new paradigm to probe properties of the mental number line. They describe two experiments which they argue to be inconsistent with the exact small number model proposed by Verguts, Fias, and Stevens [Verguts, T., Fias, W., Stevens, M. (2005). A model of exact small-number representation. Psychonomic Bulletin and (...) Review, 12, 66-80]. We discuss the data, assumptions, and conclusions of Cohen Kadosh et al.'s paper in relation to existing models of numerical cognition. (shrink)

Cohen Kadosh & Walsh (CK&W) present convincing evidence indicating the existence of notation-specific numerical representations in parietal cortex. We suggest that the same conclusions can be drawn for a particular type of numerical representation: the representation of time. Notation-dependent representations need not be limited to number but may also be extended to other magnitude-related contents processed in parietal cortex (Walsh 2003).

Cohen Kadosh & Walsh (CK&W) discuss the limitations of the behavioral, imaging, and single-cell studies related to number representation in human parietal cortex. The limitations of the imaging studies are grossly underestimated, particularly those using adaptation paradigms, and the problem of establishing a link between single-cell studies and imaging is not even addressed. Monkey functional magnetic resonance imaging (fMRI), however, provides a solution to these problems.

Cohen Kadosh & Walsh (CK&W) argue that recent findings challenge the hypothesis of abstract numerical representations. Here we show that because, like many other authors in the field, they rely on inaccurate definitions of abstract and non-abstract representations, CK&W fail to provide compelling evidence against the abstract view.

Cohen Kadosh & Walsh (CK&W) argue that numerical representation is primarily non-abstract. However, in their target article they failed to consider recent behavioral priming experiments. These priming experiments provide evidence for an abstract numerical representation under automatic conditions.

We argue that Cohen Kadosh & Walsh's (CK&W's) definitions of neural coding and of abstract representations are overly shallow, influenced by classical cognitive psychology views of modularity and seriality of information processing, and incompatible with the current knowledge on principles of neural coding. As they stand, the proposed dichotomies are not very useful heuristic tools to guide our research towards a better understanding of the neural computations underlying the processing of numerical quantity in the parietal cortex.

The target article by Cohen Kadosh & Walsh (CK&W) raises questions as to the precise nature of the notion of abstractness that is intended. We note that there are various uses of the term, and also more generally in mathematics, and suggest that abstractness is not an all-or-nothing property as the authors suggest. An alternative possibility raised by the analysis of numerical representation into automatic and intentional codes is suggested.

Much evidence cited by Cohen Kadosh & Walsh (CK&W) in support of their notation-specific representation hypothesis is based on tasks requiring automatic number processing. Several of these findings can be alternatively explained by differential expertise in mapping numerical symbols onto semantic magnitude representations. The importance of considering symbol-referent mapping expertise in theories on numerical representations is highlighted.

I challenge two points in Cohen Kadosh & Walsh's (CK & W) argument: First, the definition of abstraction is too restricted; second, the distinction between representations and operations is too clear-cut. For example, taking Jean Piaget's I propose that another way to avoid orthodoxy in the field of numerical cognition is to consider inhibition as an alternative idea of abstraction.

We challenge the arguments of Cohen Kadosh & Walsh (CK&W) on two grounds. First, interactions between number form (e.g., notation, format, modality) and an experimental factor do not show that the notations/formats/modalities are processed separately. Second, we discuss evidence that numbers are coded abstractly, also when not required by task demands and processed unintentionally, thus challenging the authors' dual-code account.

The theory put forward by Cohen Kadosh & Walsh (CK&W) proposing that semantic representations of numerical magnitude in the parietal cortex are format-specific, does not specify how these representations might be constructed over the course of learning and development. The developmental predictions of the non-abstract theory are discussed and the need for a developmental perspective on the abstract versus non-abstract question highlighted.

The dual-code proposal of number representation put forward by Cohen Kadosh & Walsh (CK&W) accounts for only a fraction of the many modes of numerical abstraction. Contrary to their proposal, robust data from human infants and nonhuman animals indicate that abstract numerical representations are psychologically primitive. Additionally, much of the behavioral and neural data cited to support CK&W's proposal is, in fact, neutral on the issue of numerical abstraction.

In recent years, a new generation of activists has reinvigorated debate over the public commemorative landscape. While this debate is in no way limited to statues, it frequently crystallizes around public representations of historical figures who expressed support for the oppression of certain groups or contributed to their past or present oppression. In this paper, I consider what should be done about such representations. A number of philosophers have articulated arguments for modifying or removing public monuments. Joanna Burch-Brown (2017) grounds (...) her argument for removal in what I call the “honorific” function of such representations—the ways in which they express and tend to cultivate admiration for their subjects. In the first two sections of the paper, I develop a novel argument for modifying these representations based on this insight. I argue that leaving such representations unmodified in the public space tends to undermine the dignity of members of oppressed groups as well as their assurance that society and government are committed to their rights and constitutional entitlements. In the paper’s third section, I develop a “balancing test” for determining whether the relevant moral and pragmatic considerations favor making a particular representation inaccessible to the public, or recontextualizing it for public consumption. Unlike some of the existing philosophical treatments of honorific representations that focus on particular monuments, this balancing test is designed for general application to any honorific representation that satisfies the presumptive case for modification. To conclude, I offer some reasons why weak forms of recontextualization that do not involve altering institutional context may often be an insufficient remedy for the problems I describe. (shrink)

The concept of acting intentionally is an important nexus where ‘theory of mind’ and moral judgment meet. Preschool children’s judgments of intentional action show a valence-driven asymmetry. Children say that a foreseen but disavowed side-effect is brought about 'on purpose' when the side-effect itself is morally bad but not when it is morally good. This is the first demonstration in preschoolers that moral judgment influences judgments of ‘on-purpose’ (as opposed to purpose influencing moral judgment). Judgments of intentional action are usually (...) assumed to be purely factual. That these judgments are sometimes partly normative — even in preschoolers — challenges current understanding. Young children’s judgments regarding foreseen side-effects depend upon whether the children process the idea that the character does not care about the side-effect. As soon as preschoolers effectively process the ‘theory of mind’ concept, NOT CARE THAT P, children show the side-effect effect.idea.. (shrink)

The motivational constraint on normative reasons says that a consideration is a normative reason for an agent to act only if it is logically possible for the agent to act for that reason, or at least to be moved so to act. The claim figures Zelig-like in philosophical debates about practical reasons: on hand, occasionally prominent, but never the focus of discussion. However, because it is entailed by a number of prominent views about normative reasons—including various forms of internalism and (...) some views that closely connect reasons to good practical reasoning—its truth or falsehood has important implications. Mark Schroeder (2007) and Julia Markovits (2014) have recently criticized the Motivational Constraint on the grounds of so-called “elusive reasons”: reasons for some agent to act that are such that it is logically impossible both that they are normative reasons for that agent and the agent is moved to act for those reasons. In response, a number of philosophers (Sinclair 2016; Ridge and McKeever 2012; Paakkunainen 2017) have attempted to reconcile blindspot reasons with the motivational constraint. My aim in this paper is to show that these conciliatory strategies fail to overcome the challenge posed by elusive reasons. First, I examine each strategy and argue that it unsuccessful on its own terms. Second, I adduce another type of elusive reason not heretofore discussed in the literature, and I argue that these strategies also cannot make this kind of reason consistent with the motivational constraint. Finally, I defend the existence of this kind of reason against an important objection. (shrink)

Corporate social responsibility (CSR) is a dramatically expanding area of activity for managers and academics. Consumer demand for responsibly produced and fair trade goods is swelling, resulting in increased demands for CSR activity and information. Assets under professional management and invested with a social responsibility focus have also grown dramatically over the last 10 years. Investors choosing social responsibility investment strategies require access to information not provided through traditional financial statements and analyses. At the same time, a group of mainstream (...) institutional investors has encouraged a movement to incorporate environmental, social, and governance information into equity analysis, and multi-stakeholder groups have supported enhanced business reporting on these issues. The majority of research in this area has been performed on European and Australian firms. We expand on this literature by exploring the CSR disclosure practices of a size- and industry-stratified sample of 50 publicly traded U.S. firms, performing a content analysis on the complete identifiable public information portfolio provided by these firms during 2004. CSR activity was disclosed by most firms in the sample, and was included in nearly half of public disclosures made during that year by the sample firms. Areas of particular emphasis are community matters, health and safety, diversity and human resources (HR) matters, and environmental programs. The primary venues of disclosure are mass media releases such as corporate websites and press releases, followed closely by disclosures contained in mandatory filings. Consistent with prior research, we identify industry effects in terms of content, emphasis, and reporting format choices. Unlike prior research, we can offer only mixed evidence on the existence of a size effect. The disclosure frequency and emphasis is significantly different for the largest one-fifth of the firms, but no identifiable trends are present within the rest of the sample. There are, however, identifiable size effects with respect to reporting format choice. Use of websites is positively related to firm size, while the use of mandatory filings is negatively related to firm size. Finally, and also consistent with prior literature, we document a generally self-laudatory tone in the content of CSR disclosures for the sample firms. (shrink)